BDBM50201320 1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(3,5-dimethylphenyl)urea::CHEMBL231309

SMILES: Cc1cc(C)cc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)c1

InChI Key: InChIKey=FUTLNLFZIZUFGB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201320 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Cc1cc(C)cc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C22H20N4OS/c1-13-9-14(2)11-17(10-13)26-22(27)25-16-5-3-15(4-6-16)18-12-28-19-7-8-24-21(23)20(18)19/h3-12H,1-2H3,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201320 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...) Show SMILES Cc1cc(C)cc(NC(=O)Nc2ccc(cc2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C22H20N4OS/c1-13-9-14(2)11-17(10-13)26-22(27)25-16-5-3-15(4-6-16)18-12-28-19-7-8-24-21(23)20(18)19/h3-12H,1-2H3,(H2,23,24)(H2,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair