BDBM50201324 1-(3-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-m-tolylurea::CHEMBL231454

SMILES: Cc1cccc(NC(=O)Nc2cccc(c2)-c2csc3ccnc(N)c23)c1

InChI Key: InChIKey=ZHDDXXTZBWXLRG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201324 (1-(3-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-m...) Show SMILES Cc1cccc(NC(=O)Nc2cccc(c2)-c2csc3ccnc(N)c23)c1 Show InChI InChI=1S/C21H18N4OS/c1-13-4-2-6-15(10-13)24-21(26)25-16-7-3-5-14(11-16)17-12-27-18-8-9-23-20(22)19(17)18/h2-12H,1H3,(H2,22,23)(H2,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair