BDBM50201328 1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-1-methyl-3-m-tolylurea::CHEMBL231356

SMILES: CN(C(=O)Nc1cccc(C)c1)c1ccc(cc1)-c1csc2ccnc(N)c12

InChI Key: InChIKey=VLPOVGNNZATENW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201328   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201328 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-1-m...) Show SMILES CN(C(=O)Nc1cccc(C)c1)c1ccc(cc1)-c1csc2ccnc(N)c12 Show InChI InChI=1S/C22H20N4OS/c1-14-4-3-5-16(12-14)25-22(27)26(2)17-8-6-15(7-9-17)18-13-28-19-10-11-24-21(23)20(18)19/h3-13H,1-2H3,(H2,23,24)(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair