BDBM50201329 1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-cyclohexylurea::CHEMBL231415

SMILES: Nc1nccc2scc(-c3ccc(NC(=O)NC4CCCCC4)cc3)c12

InChI Key: InChIKey=COIXHPWKDBPYBV-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201329   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201329 (1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-c...) Show SMILES Nc1nccc2scc(-c3ccc(NC(=O)NC4CCCCC4)cc3)c12 Show InChI InChI=1S/C20H22N4OS/c21-19-18-16(12-26-17(18)10-11-22-19)13-6-8-15(9-7-13)24-20(25)23-14-4-2-1-3-5-14/h6-12,14H,1-5H2,(H2,21,22)(H2,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	491	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 1246-9 (2007) Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS
					More data for this Ligand-Target Pair