null

SMILES: Cc1noc(NCc2ccncc2)c1C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=WJZJOYFICBHWRB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50201364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201364 (3-methyl-5-(pyridin-4-ylmethylamino)-N-(4-(trifluo...) Show SMILES Cc1noc(NCc2ccncc2)c1C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H15F3N4O2/c1-11-15(17(27-25-11)23-10-12-6-8-22-9-7-12)16(26)24-14-4-2-13(3-5-14)18(19,20)21/h2-9,23H,10H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by cell-based assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201364 (3-methyl-5-(pyridin-4-ylmethylamino)-N-(4-(trifluo...) Show SMILES Cc1noc(NCc2ccncc2)c1C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H15F3N4O2/c1-11-15(17(27-25-11)23-10-12-6-8-22-9-7-12)16(26)24-14-4-2-13(3-5-14)18(19,20)21/h2-9,23H,10H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50201364 (3-methyl-5-(pyridin-4-ylmethylamino)-N-(4-(trifluo...) Show SMILES Cc1noc(NCc2ccncc2)c1C(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H15F3N4O2/c1-11-15(17(27-25-11)23-10-12-6-8-22-9-7-12)16(26)24-14-4-2-13(3-5-14)18(19,20)21/h2-9,23H,10H2,1H3,(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair