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SMILES: Clc1cccc(NC(=O)c2cccc3CC(=O)Nc23)c1

InChI Key: InChIKey=WFLIPNHMDZOSHU-UHFFFAOYSA-N

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201478   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50201478
PNG
(CHEMBL239594 | N-(3-chlorophenyl)-2-oxoindoline-7-...)
Show SMILES Clc1cccc(NC(=O)c2cccc3CC(=O)Nc23)c1
Show InChI InChI=1S/C15H11ClN2O2/c16-10-4-2-5-11(8-10)17-15(20)12-6-1-3-9-7-13(19)18-14(9)12/h1-6,8H,7H2,(H,17,20)(H,18,19)
PDB
MMDB

KEGG

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 397n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd

Curated by ChEMBL


Assay Description
Binding affinity to mGluR5

Bioorg Med Chem Lett 17: 1302-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.006
BindingDB Entry DOI: 10.7270/Q2H41R3G
More data for this
Ligand-Target Pair