BDBM50201661 2-(2-(2-chlorophenyl)ethynyl)-6-methylpyridine::CHEMBL415083

SMILES: Cc1cccc(n1)C#Cc1ccccc1Cl

InChI Key: InChIKey=GFSPITZTVJNUPB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50201661 (2-(2-(2-chlorophenyl)ethynyl)-6-methylpyridine | C...) Show SMILES Cc1cccc(n1)C#Cc1ccccc1Cl Show InChI InChI=1S/C14H10ClN/c1-11-5-4-7-13(16-11)10-9-12-6-2-3-8-14(12)15/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at mGluR5 by FLIPR				Bioorg Med Chem Lett 17: 1307-11 (2007) Article DOI: 10.1016/j.bmcl.2006.12.033 BindingDB Entry DOI: 10.7270/Q2V987R8
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50201661 (2-(2-(2-chlorophenyl)ethynyl)-6-methylpyridine | C...) Show SMILES Cc1cccc(n1)C#Cc1ccccc1Cl Show InChI InChI=1S/C14H10ClN/c1-11-5-4-7-13(16-11)10-9-12-6-2-3-8-14(12)15/h2-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGlu5 receptor				Bioorg Med Chem Lett 17: 1307-11 (2007) Article DOI: 10.1016/j.bmcl.2006.12.033 BindingDB Entry DOI: 10.7270/Q2V987R8
					More data for this Ligand-Target Pair