BDBM50201667 (E)-1-(1-methyl-4-oxoimidazolidin-2-ylidene)-3-(pyridin-3-yl)urea::CHEMBL239802

SMILES: Cn1cc(O)nc1NC(=O)Nc1cccnc1

InChI Key: InChIKey=GXFOWPYTHQYGTI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50201667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50201667 ((E)-1-(1-methyl-4-oxoimidazolidin-2-ylidene)-3-(py...) Show SMILES Cn1cc(O)nc1NC(=O)Nc1cccnc1 Show InChI InChI=1S/C10H11N5O2/c1-15-6-8(16)13-9(15)14-10(17)12-7-3-2-4-11-5-7/h2-6,16H,1H3,(H2,12,13,14,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGlu5 receptor				Bioorg Med Chem Lett 17: 1307-11 (2007) Article DOI: 10.1016/j.bmcl.2006.12.033 BindingDB Entry DOI: 10.7270/Q2V987R8
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50201667 ((E)-1-(1-methyl-4-oxoimidazolidin-2-ylidene)-3-(py...) Show SMILES Cn1cc(O)nc1NC(=O)Nc1cccnc1 Show InChI InChI=1S/C10H11N5O2/c1-15-6-8(16)13-9(15)14-10(17)12-7-3-2-4-11-5-7/h2-6,16H,1H3,(H2,12,13,14,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Antagonist activity at mGluR5 by FLIPR				Bioorg Med Chem Lett 17: 1307-11 (2007) Article DOI: 10.1016/j.bmcl.2006.12.033 BindingDB Entry DOI: 10.7270/Q2V987R8
					More data for this Ligand-Target Pair