BDBM50201767 CHEMBL3890887

SMILES: CCc1ccc(cc1)-c1cc(ncn1)C(=O)Nc1ccc(Oc2ccnc(c2)C(=O)NC)c(F)c1

InChI Key: InChIKey=FPARNZFRMRRZMI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201767 (CHEMBL3890887) Show SMILES CCc1ccc(cc1)-c1cc(ncn1)C(=O)Nc1ccc(Oc2ccnc(c2)C(=O)NC)c(F)c1 Show InChI InChI=1S/C26H22FN5O3/c1-3-16-4-6-17(7-5-16)21-14-23(31-15-30-21)26(34)32-18-8-9-24(20(27)12-18)35-19-10-11-29-22(13-19)25(33)28-2/h4-15H,3H2,1-2H3,(H,28,33)(H,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jiangxi Science& Technology Normal University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) by mobility shift/LanthaScreen assay				Bioorg Med Chem 24: 6166-6173 (2016) Article DOI: 10.1016/j.bmc.2016.09.021 BindingDB Entry DOI: 10.7270/Q2XD13PQ
					More data for this Ligand-Target Pair