BDBM50203690 1-(4-bromophenyl)-2-ethylthio-5-(4-methylsulfonylphenyl)imidazole::CHEMBL243797

SMILES: CCSc1ncc(-c2ccc(cc2)S(C)(=O)=O)n1-c1ccc(Br)cc1

InChI Key: InChIKey=AQIJDUMIYPEJNZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50203690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase-2 (COX-2) (Mus musculus (Mouse))	BDBM50203690 (1-(4-bromophenyl)-2-ethylthio-5-(4-methylsulfonylp...) Show SMILES CCSc1ncc(-c2ccc(cc2)S(C)(=O)=O)n1-c1ccc(Br)cc1 Show InChI InChI=1S/C18H17BrN2O2S2/c1-3-24-18-20-12-17(21(18)15-8-6-14(19)7-9-15)13-4-10-16(11-5-13)25(2,22)23/h4-12H,3H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tehran University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of mouse COX2				Bioorg Med Chem 15: 1976-82 (2007) Article DOI: 10.1016/j.bmc.2006.12.041 BindingDB Entry DOI: 10.7270/Q2S75FZ0
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep))	BDBM50203690 (1-(4-bromophenyl)-2-ethylthio-5-(4-methylsulfonylp...) Show SMILES CCSc1ncc(-c2ccc(cc2)S(C)(=O)=O)n1-c1ccc(Br)cc1 Show InChI InChI=1S/C18H17BrN2O2S2/c1-3-24-18-20-12-17(21(18)15-8-6-14(19)7-9-15)13-4-10-16(11-5-13)25(2,22)23/h4-12H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tehran University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of ovine COX1				Bioorg Med Chem 15: 1976-82 (2007) Article DOI: 10.1016/j.bmc.2006.12.041 BindingDB Entry DOI: 10.7270/Q2S75FZ0
					More data for this Ligand-Target Pair