BDBM50203738 CHEMBL3934291

SMILES: COc1ccc(F)c(C(=O)N2CCC(F)(F)[C@H](C2)Oc2ccc3ccccc3n2)c1F

InChI Key: InChIKey=YYBYVQOKVCZREF-KRWDZBQOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50203738 (CHEMBL3934291) Show SMILES COc1ccc(F)c(C(=O)N2CCC(F)(F)[C@H](C2)Oc2ccc3ccccc3n2)c1F |r| Show InChI InChI=1S/C22H18F4N2O3/c1-30-16-8-7-14(23)19(20(16)24)21(29)28-11-10-22(25,26)17(12-28)31-18-9-6-13-4-2-3-5-15(13)27-18/h2-9,17H,10-12H2,1H3/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of (2S)-N-(2-pyrrol-1-ylphenyl)-1-[2-[1-(tritritiomethyl)benzimidazol-2-yl]sulfanylacetyl]pyrrolidine-2-carboxamide from human OX2 recep...				Bioorg Med Chem Lett 26: 5809-5814 (2016) Article DOI: 10.1016/j.bmcl.2016.10.019 BindingDB Entry DOI: 10.7270/Q2MS3VRG
					More data for this Ligand-Target Pair