Found 19 hits for monomerid = 50204493 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Fatty-acid amide hydrolase 1 (aa 30-579)
(Rattus norvegicus (rat)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown |
J Med Chem 50: 1058-68 (2007)
Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
J Med Chem 54: 2529-91 (2011)
Article DOI: 10.1021/jm1013693 BindingDB Entry DOI: 10.7270/Q24M95PH |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Inhibition of FAAH |
J Med Chem 51: 7327-43 (2009)
Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 (aa 30-579)
(Rattus norvegicus (rat)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH |
Bioorg Med Chem Lett 18: 5842-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 (aa 30-579)
(Rattus norvegicus (rat)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Acyl-CoA: cholesterol acyltransferase (ACAT)
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of TGH |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Acyl-CoA: cholesterol acyltransferase (ACAT)
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of TGH |
J Med Chem 50: 1058-68 (2007)
Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G |
More data for this Ligand-Target Pair | |
Neutral cholesterol ester hydrolase 1
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of KIAA1363 |
J Med Chem 50: 1058-68 (2007)
Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 (aa 30-579)
(Rattus norvegicus (rat)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH expressed in Escherichia coli |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Neutral cholesterol ester hydrolase 1
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of KIAA1363 hydrolase |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Acyl-CoA: cholesterol acyltransferase (ACAT)
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Chemical Biology
Curated by ChEMBL
| Assay Description Inhibition of TGH |
J Med Chem 51: 4392-403 (2008)
Article DOI: 10.1021/jm800136b BindingDB Entry DOI: 10.7270/Q26D5TW3 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown |
J Med Chem 50: 1058-68 (2007)
Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G |
More data for this Ligand-Target Pair | |
Neutral cholesterol ester hydrolase 1
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of KIAA1363 |
J Med Chem 51: 937-47 (2008)
Article DOI: 10.1021/jm701210y BindingDB Entry DOI: 10.7270/Q2QV3NCP |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human FAAH |
Bioorg Med Chem Lett 18: 2109-13 (2008)
Article DOI: 10.1016/j.bmcl.2008.01.091 BindingDB Entry DOI: 10.7270/Q2708287 |
More data for this Ligand-Target Pair | |
Fatty-acid amide hydrolase 1 (aa 30-579)
(Rattus norvegicus (rat)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of rat FAAH |
Bioorg Med Chem Lett 18: 5842-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8 |
More data for this Ligand-Target Pair | |
Acyl-CoA: cholesterol acyltransferase (ACAT)
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of TGH (unknown origin) |
Bioorg Med Chem Lett 18: 5842-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8 |
More data for this Ligand-Target Pair | |
Sn1-specific diacylglycerol lipase alpha
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Leiden University
Curated by ChEMBL
| Assay Description Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assay |
J Med Chem 58: 9742-53 (2015)
Article DOI: 10.1021/acs.jmedchem.5b01627 BindingDB Entry DOI: 10.7270/Q2D50QZ9 |
More data for this Ligand-Target Pair | |
Neutral cholesterol ester hydrolase 1
(Homo sapiens (Human)) | BDBM50204493
(1-(oxazol-2-yl)-7-phenylheptan-1-one | CHEMBL22012...)Show InChI InChI=1S/C16H19NO2/c18-15(16-17-12-13-19-16)11-7-2-1-4-8-14-9-5-3-6-10-14/h3,5-6,9-10,12-13H,1-2,4,7-8,11H2 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description Inhibition of KIAA1363 (unknown origin) |
Bioorg Med Chem Lett 18: 5842-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.06.084 BindingDB Entry DOI: 10.7270/Q2DN44V8 |
More data for this Ligand-Target Pair | |