BDBM50204592 6-(3-methoxy-4-(2-(piperidin-1-yl)ethoxy)phenyl)-5-phenyl-N-(2-(piperazin-1-yl)ethyl)furo[2,3-d]pyrimidin-4-amine::CHEMBL394490

SMILES: COc1cc(ccc1OCCN1CCCCC1)-c1oc2ncnc(NCCN3CCNCC3)c2c1-c1ccccc1

InChI Key: InChIKey=PQXQJSMNKNNINY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204592   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50204592 (6-(3-methoxy-4-(2-(piperidin-1-yl)ethoxy)phenyl)-5...) Show SMILES COc1cc(ccc1OCCN1CCCCC1)-c1oc2ncnc(NCCN3CCNCC3)c2c1-c1ccccc1 Show InChI InChI=1S/C32H40N6O3/c1-39-27-22-25(10-11-26(27)40-21-20-37-15-6-3-7-16-37)30-28(24-8-4-2-5-9-24)29-31(35-23-36-32(29)41-30)34-14-19-38-17-12-33-13-18-38/h2,4-5,8-11,22-23,33H,3,6-7,12-21H2,1H3,(H,34,35,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lck				Bioorg Med Chem Lett 17: 2305-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.057 BindingDB Entry DOI: 10.7270/Q2697365
					More data for this Ligand-Target Pair
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50204592 (6-(3-methoxy-4-(2-(piperidin-1-yl)ethoxy)phenyl)-5...) Show SMILES COc1cc(ccc1OCCN1CCCCC1)-c1oc2ncnc(NCCN3CCNCC3)c2c1-c1ccccc1 Show InChI InChI=1S/C32H40N6O3/c1-39-27-22-25(10-11-26(27)40-21-20-37-15-6-3-7-16-37)30-28(24-8-4-2-5-9-24)29-31(35-23-36-32(29)41-30)34-14-19-38-17-12-33-13-18-38/h2,4-5,8-11,22-23,33H,3,6-7,12-21H2,1H3,(H,34,35,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	586	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Ack1				Bioorg Med Chem Lett 17: 2305-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.057 BindingDB Entry DOI: 10.7270/Q2697365
					More data for this Ligand-Target Pair