BDBM50205500 CHEMBL3933984

SMILES: Fc1cnccc1-c1nnn(CC(=O)Nc2ccc(cn2)-c2ccccc2)c1-c1ccccc1

InChI Key: InChIKey=HIKKUKRREAFDFJ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205500   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-serine O-palmitoleoyltransferase porcupine (Mus musculus)	BDBM50205500 (CHEMBL3933984) Show SMILES Fc1cnccc1-c1nnn(CC(=O)Nc2ccc(cn2)-c2ccccc2)c1-c1ccccc1 Show InChI InChI=1S/C26H19FN6O/c27-22-16-28-14-13-21(22)25-26(19-9-5-2-6-10-19)33(32-31-25)17-24(34)30-23-12-11-20(15-29-23)18-7-3-1-4-8-18/h1-16H,17H2,(H,29,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.130	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair