BDBM50206840 CHEMBL413002::ethyl 4-((3,5-bis(trifluoromethyl)phenyl)(2-(3-methoxy-3-oxopropyl)-2H-tetrazol-5-yl)methyl)-2-ethyl-6-(trifluoromethyl)-3,4-dihydroquinoxaline-1(2H)-carboxylate

SMILES: CCOC(=O)N1C(CC)CN(C(c2nnn(CCC(=O)OC)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F

InChI Key: InChIKey=JOYAUBZDITVLEK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50206840 (CHEMBL413002 | ethyl 4-((3,5-bis(trifluoromethyl)p...) Show SMILES CCOC(=O)N1C(CC)CN(C(c2nnn(CCC(=O)OC)n2)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2cc(ccc12)C(F)(F)F |w:11.10,6.6| Show InChI InChI=1S/C28H27F9N6O4/c1-4-19-14-41(21-13-16(26(29,30)31)6-7-20(21)43(19)25(45)47-5-2)23(24-38-40-42(39-24)9-8-22(44)46-3)15-10-17(27(32,33)34)12-18(11-15)28(35,36)37/h6-7,10-13,19,23H,4-5,8-9,14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma Curated by ChEMBL					Assay Description Inhibition of CETP in human plasma				Bioorg Med Chem Lett 17: 2608-13 (2007) Article DOI: 10.1016/j.bmcl.2007.01.112 BindingDB Entry DOI: 10.7270/Q2ZG6RXM
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