BDBM50208358 CHEMBL3885409

SMILES: COC(=O)c1ccc(cc1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(c(F)c(C)c2Cl)[N+]([O-])=O)c1

InChI Key: InChIKey=FUNIBWOVENEVSY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50208358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50208358 (CHEMBL3885409) Show SMILES COC(=O)c1ccc(cc1)-c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(c(F)c(C)c2Cl)[N+]([O-])=O)c1 Show InChI InChI=1S/C27H26ClFN4O5/c1-16-24(28)20(15-23(25(16)29)33(36)37)26(34)30-21-14-19(17-4-6-18(7-5-17)27(35)38-3)8-9-22(21)32-12-10-31(2)11-13-32/h4-9,14-15H,10-13H2,1-3H3,(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of 10mer-Thr-FAM probe binding to human WDR5 after 2 hrs by fluorescence polarization assay				Eur J Med Chem 124: 480-489 (2016) Article DOI: 10.1016/j.ejmech.2016.08.036 BindingDB Entry DOI: 10.7270/Q2251M6G
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