Found 3 hits for monomerid = 50208925 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine/threonine-protein kinase c-TAK1
(Homo sapiens (Human)) | BDBM50208925
(CHEMBL3883548)Show InChI InChI=1S/C19H23N5O/c1-19(2)15-12-21-18(22-13-7-6-10-20-11-13)23-16(15)24(17(19)25)14-8-4-3-5-9-14/h6-7,10-12,14H,3-5,8-9H2,1-2H3,(H,21,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 346 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assay |
Bioorg Med Chem Lett 27: 114-120 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.068 BindingDB Entry DOI: 10.7270/Q2N018JC |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase c-TAK1
(Homo sapiens (Human)) | BDBM50208925
(CHEMBL3883548)Show InChI InChI=1S/C19H23N5O/c1-19(2)15-12-21-18(22-13-7-6-10-20-11-13)23-16(15)24(17(19)25)14-8-4-3-5-9-14/h6-7,10-12,14H,3-5,8-9H2,1-2H3,(H,21,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 346 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description Inhibition of MARK3 (unknown origin) |
Bioorg Med Chem Lett 27: 109-113 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.066 BindingDB Entry DOI: 10.7270/Q20867B1 |
More data for this Ligand-Target Pair | |
MAP/microtubule affinity-regulating kinase 4
(Homo sapiens (Human)) | BDBM50208925
(CHEMBL3883548)Show InChI InChI=1S/C19H23N5O/c1-19(2)15-12-21-18(22-13-7-6-10-20-11-13)23-16(15)24(17(19)25)14-8-4-3-5-9-14/h6-7,10-12,14H,3-5,8-9H2,1-2H3,(H,21,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck& Co.
Curated by ChEMBL
| Assay Description Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by Alph... |
Bioorg Med Chem Lett 27: 114-120 (2017)
Article DOI: 10.1016/j.bmcl.2016.08.068 BindingDB Entry DOI: 10.7270/Q2N018JC |
More data for this Ligand-Target Pair | |