Found 4 hits for monomerid = 50209401 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Liver carboxylesterase 1
(Homo sapiens (Human)) | BDBM50209401
(1,2-bis[4-(trifluoromethyl)phenyl]ethane-1,2-dione...)Show SMILES FC(F)(F)c1ccc(cc1)C(=O)C(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C16H8F6O2/c17-15(18,19)11-5-1-9(2-6-11)13(23)14(24)10-3-7-12(8-4-10)16(20,21)22/h1-8H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of human carboxylesterase 1 |
Bioorg Med Chem 15: 3801-17 (2007)
Article DOI: 10.1016/j.bmc.2007.03.012 BindingDB Entry DOI: 10.7270/Q29G5MGV |
More data for this Ligand-Target Pair | |
Cocaine esterase
(Homo sapiens (Human)) | BDBM50209401
(1,2-bis[4-(trifluoromethyl)phenyl]ethane-1,2-dione...)Show SMILES FC(F)(F)c1ccc(cc1)C(=O)C(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C16H8F6O2/c17-15(18,19)11-5-1-9(2-6-11)13(23)14(24)10-3-7-12(8-4-10)16(20,21)22/h1-8H | NCI pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of human intestinal carboxylesterase |
Bioorg Med Chem 15: 3801-17 (2007)
Article DOI: 10.1016/j.bmc.2007.03.012 BindingDB Entry DOI: 10.7270/Q29G5MGV |
More data for this Ligand-Target Pair | |
Cholinesterase
(Homo sapiens (Human)) | BDBM50209401
(1,2-bis[4-(trifluoromethyl)phenyl]ethane-1,2-dione...)Show SMILES FC(F)(F)c1ccc(cc1)C(=O)C(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C16H8F6O2/c17-15(18,19)11-5-1-9(2-6-11)13(23)14(24)10-3-7-12(8-4-10)16(20,21)22/h1-8H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of human BChE |
Bioorg Med Chem 15: 3801-17 (2007)
Article DOI: 10.1016/j.bmc.2007.03.012 BindingDB Entry DOI: 10.7270/Q29G5MGV |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Homo sapiens (Human)) | BDBM50209401
(1,2-bis[4-(trifluoromethyl)phenyl]ethane-1,2-dione...)Show SMILES FC(F)(F)c1ccc(cc1)C(=O)C(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C16H8F6O2/c17-15(18,19)11-5-1-9(2-6-11)13(23)14(24)10-3-7-12(8-4-10)16(20,21)22/h1-8H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of human AChE |
Bioorg Med Chem 15: 3801-17 (2007)
Article DOI: 10.1016/j.bmc.2007.03.012 BindingDB Entry DOI: 10.7270/Q29G5MGV |
More data for this Ligand-Target Pair | |