Found 4 hits for monomerid = 50209887 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50209887
((2E)-4-(dimethylamino)-N-{7-ethoxy-4-[(4-methoxy-3...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OC)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:17,t:11| Show InChI InChI=1S/C23H25N5O5/c1-5-33-20-11-15-14(9-17(20)26-22(31)7-6-8-28(2)3)23(25-13-24-15)27-16-10-19(30)21(32-4)12-18(16)29/h6-7,9-13H,5,8H2,1-4H3,(H,26,31)(H,24,25,27)/b7-6+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 379 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human VEGFR2 in presence of 1 uM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50209887
((2E)-4-(dimethylamino)-N-{7-ethoxy-4-[(4-methoxy-3...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OC)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:17,t:11| Show InChI InChI=1S/C23H25N5O5/c1-5-33-20-11-15-14(9-17(20)26-22(31)7-6-8-28(2)3)23(25-13-24-15)27-16-10-19(30)21(32-4)12-18(16)29/h6-7,9-13H,5,8H2,1-4H3,(H,26,31)(H,24,25,27)/b7-6+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human VEGFR2 in presence of 1 mM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50209887
((2E)-4-(dimethylamino)-N-{7-ethoxy-4-[(4-methoxy-3...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OC)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:17,t:11| Show InChI InChI=1S/C23H25N5O5/c1-5-33-20-11-15-14(9-17(20)26-22(31)7-6-8-28(2)3)23(25-13-24-15)27-16-10-19(30)21(32-4)12-18(16)29/h6-7,9-13H,5,8H2,1-4H3,(H,26,31)(H,24,25,27)/b7-6+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human EGFR in presence of 1 mM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50209887
((2E)-4-(dimethylamino)-N-{7-ethoxy-4-[(4-methoxy-3...)Show SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OC)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C |c:17,t:11| Show InChI InChI=1S/C23H25N5O5/c1-5-33-20-11-15-14(9-17(20)26-22(31)7-6-8-28(2)3)23(25-13-24-15)27-16-10-19(30)21(32-4)12-18(16)29/h6-7,9-13H,5,8H2,1-4H3,(H,26,31)(H,24,25,27)/b7-6+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 799 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description
Inhibition of human EGFR in presence of 1 uM ATP |
Bioorg Med Chem 15: 3635-48 (2007)
Article DOI: 10.1016/j.bmc.2007.03.055
BindingDB Entry DOI: 10.7270/Q2GF0VB8 |
More data for this
Ligand-Target Pair | |
Search and Browse
