BDBM50210478 CHEMBL249326::{4-[7-dimethylaminomethyl-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl}-(3-fluorobenzyl)amine
SMILES: CN(C)Cc1ccn2c(c(nc2c1)-c1ccc(F)cc1)-c1ccnc(NCc2cccc(F)c2)n1
InChI Key: InChIKey=DBFOUULXHFMONW-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cGMP-dependent protein kinase (Eimeria tenella) | BDBM50210478 (CHEMBL249326 | {4-[7-dimethylaminomethyl-2-(4-fluo...) | UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a |
SCYNEXIS, Inc. Curated by ChEMBL | Assay Description Inhibition of Eimeria tenella cGMP-dependent protein kinase by Ten_K assay | Eur J Med Chem 42: 1334-57 (2007) Article DOI: 10.1016/j.ejmech.2007.02.006 BindingDB Entry DOI: 10.7270/Q2SB45FM | |||||||||||
More data for this Ligand-Target Pair |