BDBM50211020 CHEMBL231684::methyl 2-(biphenyl-4-yl)cycloheptanecarboxylate
SMILES: COC(=O)[C@@H]1CCCCC[C@@H]1c1ccc(cc1)-c1ccccc1
InChI Key: InChIKey=OJEXZTOASHOTIX-WOJBJXKFSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50211020 (CHEMBL231684 | methyl 2-(biphenyl-4-yl)cycloheptan...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aarhus Curated by ChEMBL | Assay Description Displacement of [125I]RTI55 from human NET expressed in COS1 cell membrane | Bioorg Med Chem 15: 4159-74 (2007) Article DOI: 10.1016/j.bmc.2007.03.069 BindingDB Entry DOI: 10.7270/Q2ZC83PB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50211020 (CHEMBL231684 | methyl 2-(biphenyl-4-yl)cycloheptan...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aarhus Curated by ChEMBL | Assay Description Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membrane | Bioorg Med Chem 15: 4159-74 (2007) Article DOI: 10.1016/j.bmc.2007.03.069 BindingDB Entry DOI: 10.7270/Q2ZC83PB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50211020 (CHEMBL231684 | methyl 2-(biphenyl-4-yl)cycloheptan...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.13E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Aarhus Curated by ChEMBL | Assay Description Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membrane | Bioorg Med Chem 15: 4159-74 (2007) Article DOI: 10.1016/j.bmc.2007.03.069 BindingDB Entry DOI: 10.7270/Q2ZC83PB | |||||||||||
More data for this Ligand-Target Pair |