Found 4 hits for monomerid = 50213940 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Matrix metalloproteinase-14 (MMP14)
(Homo sapiens (Human)) | BDBM50213940
(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)Cc1ccncc1)C(=O)NO |w:15.15| Show InChI InChI=1S/C23H27N3O7S2/c1-2-3-15-33-20-5-7-21(8-6-20)34(29,30)18-23(22(27)25-28)11-4-14-26(17-23)35(31,32)16-19-9-12-24-13-10-19/h5-10,12-13,28H,4,11,14-18H2,1H3,(H,25,27) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP14 |
Bioorg Med Chem Lett 17: 4333-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.022 BindingDB Entry DOI: 10.7270/Q2CN73K3 |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50213940
(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)Cc1ccncc1)C(=O)NO |w:15.15| Show InChI InChI=1S/C23H27N3O7S2/c1-2-3-15-33-20-5-7-21(8-6-20)34(29,30)18-23(22(27)25-28)11-4-14-26(17-23)35(31,32)16-19-9-12-24-13-10-19/h5-10,12-13,28H,4,11,14-18H2,1H3,(H,25,27) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
Bioorg Med Chem Lett 17: 4333-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.022 BindingDB Entry DOI: 10.7270/Q2CN73K3 |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50213940
(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)Cc1ccncc1)C(=O)NO |w:15.15| Show InChI InChI=1S/C23H27N3O7S2/c1-2-3-15-33-20-5-7-21(8-6-20)34(29,30)18-23(22(27)25-28)11-4-14-26(17-23)35(31,32)16-19-9-12-24-13-10-19/h5-10,12-13,28H,4,11,14-18H2,1H3,(H,25,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
Bioorg Med Chem Lett 17: 4333-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.022 BindingDB Entry DOI: 10.7270/Q2CN73K3 |
More data for this Ligand-Target Pair | |
Disintegrin and metalloproteinase domain-containing protein 17
(Homo sapiens (Human)) | BDBM50213940
(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydr...)Show SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)Cc1ccncc1)C(=O)NO |w:15.15| Show InChI InChI=1S/C23H27N3O7S2/c1-2-3-15-33-20-5-7-21(8-6-20)34(29,30)18-23(22(27)25-28)11-4-14-26(17-23)35(31,32)16-19-9-12-24-13-10-19/h5-10,12-13,28H,4,11,14-18H2,1H3,(H,25,27) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
Curated by ChEMBL
| Assay Description Inhibition of TACE by FRET assay |
Bioorg Med Chem Lett 17: 4333-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.022 BindingDB Entry DOI: 10.7270/Q2CN73K3 |
More data for this Ligand-Target Pair | |