BDBM50214901 (S)-2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)propyl)amino)methyl)phenoxy)butanoic acid::CHEMBL247749
SMILES: CC[C@H](Oc1cccc(CN(CCCOc2ccc(F)cc2)c2nc3ccccc3o2)c1)C(O)=O
InChI Key: InChIKey=FEIXPYZPYIUNRN-DEOSSOPVSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50214901 ((S)-2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.57E+3 | n/a | n/a | n/a | n/a |
Kowa Co. Curated by ChEMBL | Assay Description Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay | Bioorg Med Chem Lett 17: 4689-93 (2007) Article DOI: 10.1016/j.bmcl.2007.05.066 BindingDB Entry DOI: 10.7270/Q2J67GM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human)) | BDBM50214901 ((S)-2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Kowa Co. Curated by ChEMBL | Assay Description Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay | Bioorg Med Chem Lett 17: 4689-93 (2007) Article DOI: 10.1016/j.bmcl.2007.05.066 BindingDB Entry DOI: 10.7270/Q2J67GM5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50214901 ((S)-2-(3-((benzo[d]oxazol-2-yl(3-(4-fluorophenoxy)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a |
Kowa Co. Curated by ChEMBL | Assay Description Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay | Bioorg Med Chem Lett 17: 4689-93 (2007) Article DOI: 10.1016/j.bmcl.2007.05.066 BindingDB Entry DOI: 10.7270/Q2J67GM5 | |||||||||||
More data for this Ligand-Target Pair |