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SMILES: CN(CCc1ccccn1)CCn1c(=O)c2CN(Cc3ccc(cc3)C(F)(F)F)CCc2n(Cc2c(F)cccc2F)c1=O

InChI Key: InChIKey=RPWAWOSYDIWRBM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215179   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50215179
PNG
(1-(2,6-difluorobenzyl)-6-(4-(trifluoromethyl)benzy...)
Show SMILES CN(CCc1ccccn1)CCn1c(=O)c2CN(Cc3ccc(cc3)C(F)(F)F)CCc2n(Cc2c(F)cccc2F)c1=O
Show InChI InChI=1S/C32H32F5N5O2/c1-39(15-12-24-5-2-3-14-38-24)17-18-41-30(43)26-20-40(19-22-8-10-23(11-9-22)32(35,36)37)16-13-29(26)42(31(41)44)21-25-27(33)6-4-7-28(25)34/h2-11,14H,12-13,15-21H2,1H3
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Similars
Article
PubMed
 30n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Displacement of [125I-His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cells

Bioorg Med Chem 15: 5590-603 (2007)


Article DOI: 10.1016/j.bmc.2007.05.029
BindingDB Entry DOI: 10.7270/Q2VH5NJG
More data for this
Ligand-Target Pair