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SMILES: CN(CCc1ccccn1)CCn1c(=O)c2CN(CCc3c[nH]c4ccccc34)CCc2n(Cc2c(F)cccc2F)c1=O

InChI Key: InChIKey=VTBVXMWPFNAGBO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215180   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50215180
PNG
(6-(2-(1H-indol-3-yl)ethyl)-1-(2,6-difluorobenzyl)-...)
Show SMILES CN(CCc1ccccn1)CCn1c(=O)c2CN(CCc3c[nH]c4ccccc34)CCc2n(Cc2c(F)cccc2F)c1=O
Show InChI InChI=1S/C34H36F2N6O2/c1-39(16-13-25-7-4-5-15-37-25)19-20-41-33(43)28-22-40(17-12-24-21-38-31-11-3-2-8-26(24)31)18-14-32(28)42(34(41)44)23-27-29(35)9-6-10-30(27)36/h2-11,15,21,38H,12-14,16-20,22-23H2,1H3
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Similars
Article
PubMed
 515n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Displacement of [125I-His5,D-Tyr6]GnRH from human cloned GnRH receptor transfected in COS7 cells

Bioorg Med Chem 15: 5590-603 (2007)


Article DOI: 10.1016/j.bmc.2007.05.029
BindingDB Entry DOI: 10.7270/Q2VH5NJG
More data for this
Ligand-Target Pair