BDBM50215376 CHEMBL362228

SMILES: OC(=O)C1(CC(=O)Nc2cccc(OCc3ccc4ccc(F)cc4n3)c2)CCCCC1

InChI Key: InChIKey=PQBWZIFOPYSMTQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50215376   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50215376 (CHEMBL362228) Show SMILES OC(=O)C1(CC(=O)Nc2cccc(OCc3ccc4ccc(F)cc4n3)c2)CCCCC1 Show InChI InChI=1S/C25H25FN2O4/c26-18-9-7-17-8-10-20(27-22(17)13-18)16-32-21-6-4-5-19(14-21)28-23(29)15-25(24(30)31)11-2-1-3-12-25/h4-10,13-14H,1-3,11-12,15-16H2,(H,28,29)(H,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro for antagonistic activity against LTD4 receptor in guinea pig ileum				Bioorg Med Chem Lett 8: 965-70 (1999) BindingDB Entry DOI: 10.7270/Q2V123XT
					More data for this Ligand-Target Pair