BDBM50215969 CHEMBL57924
SMILES: COc1c(I)cc(I)cc1C(=O)Nc1cc(C)c(cc1Cl)C(C#N)c1ccc(Cl)cc1
InChI Key: InChIKey=CPNSPZQMLFBXQY-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sporulation kinase A (Bacillus subtilis (strain 168)) | BDBM50215969![]() (CHEMBL57924) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of histidine protein kinase (KinA) phosphorylation in the presence of response regulator (Spo0F) | Bioorg Med Chem Lett 8: 1923-8 (1998) BindingDB Entry DOI: 10.7270/Q27S7QZM | |||||||||||
More data for this Ligand-Target Pair |