null

SMILES: CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)s1

InChI Key: InChIKey=VFSSAOMALPZMID-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217890 (3-[(5-chlorothien-2-yl)sulfonyl]-1-(1-methylpiperi...) Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)s1 |w:5.7| Show InChI InChI=1S/C17H18ClN3O2S2/c1-20-9-3-4-12(10-20)21-11-14(13-5-2-8-19-17(13)21)25(22,23)16-7-6-15(18)24-16/h2,5-8,11-12H,3-4,9-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217890 (3-[(5-chlorothien-2-yl)sulfonyl]-1-(1-methylpiperi...) Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)s1 |w:5.7| Show InChI InChI=1S/C17H18ClN3O2S2/c1-20-9-3-4-12(10-20)21-11-14(13-5-2-8-19-17(13)21)25(22,23)16-7-6-15(18)24-16/h2,5-8,11-12H,3-4,9-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Binding affinity to 5HT6 receptor				Eur J Med Chem 45: 3911-5 (2010) Article DOI: 10.1016/j.ejmech.2010.05.045 BindingDB Entry DOI: 10.7270/Q27945XK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217890 (3-[(5-chlorothien-2-yl)sulfonyl]-1-(1-methylpiperi...) Show SMILES CN1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccc(Cl)s1 |w:5.7| Show InChI InChI=1S/C17H18ClN3O2S2/c1-20-9-3-4-12(10-20)21-11-14(13-5-2-8-19-17(13)21)25(22,23)16-7-6-15(18)24-16/h2,5-8,11-12H,3-4,9-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair