BDBM50218161 CHEMBL52783

SMILES: Clc1cccc2N(CCc12)C(=O)Nc1ccc(OCc2ccccn2)nc1

InChI Key: InChIKey=XLSCFWFTYUTRTQ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218161   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50218161 (CHEMBL52783) Show SMILES Clc1cccc2N(CCc12)C(=O)Nc1ccc(OCc2ccccn2)nc1 Show InChI InChI=1S/C20H17ClN4O2/c21-17-5-3-6-18-16(17)9-11-25(18)20(26)24-14-7-8-19(23-12-14)27-13-15-4-1-2-10-22-15/h1-8,10,12H,9,11,13H2,(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by [3H]mesulergine displacement.				Bioorg Med Chem Lett 10: 1867-70 (2000) BindingDB Entry DOI: 10.7270/Q2SF2ZB2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50218161 (CHEMBL52783) Show SMILES Clc1cccc2N(CCc12)C(=O)Nc1ccc(OCc2ccccn2)nc1 Show InChI InChI=1S/C20H17ClN4O2/c21-17-5-3-6-18-16(17)9-11-25(18)20(26)24-14-7-8-19(23-12-14)27-13-15-4-1-2-10-22-15/h1-8,10,12H,9,11,13H2,(H,24,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned 5-hydroxytryptamine 2B receptor of HEK293 cells by [3H]5-HT displacement.				Bioorg Med Chem Lett 10: 1867-70 (2000) BindingDB Entry DOI: 10.7270/Q2SF2ZB2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50218161 (CHEMBL52783) Show SMILES Clc1cccc2N(CCc12)C(=O)Nc1ccc(OCc2ccccn2)nc1 Show InChI InChI=1S/C20H17ClN4O2/c21-17-5-3-6-18-16(17)9-11-25(18)20(26)24-14-7-8-19(23-12-14)27-13-15-4-1-2-10-22-15/h1-8,10,12H,9,11,13H2,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 1867-70 (2000) BindingDB Entry DOI: 10.7270/Q2SF2ZB2
					More data for this Ligand-Target Pair