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BDBM50218296 5-chloro-N-((3R,4S)-4-(4-(2-oxopyridin-1(2H)-yl)benzamido)-1-(pyrrolidine-1-carbonyl)pyrrolidin-3-yl)thiophene-2-carboxamide::CHEMBL442079

SMILES: Clc1ccc(s1)C(=O)N[C@@H]1CN(C[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O)C(=O)N1CCCC1

InChI Key: InChIKey=GMHVYIPEQITJMR-VQTJNVASSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218296   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50218296
PNG
(5-chloro-N-((3R,4S)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Show SMILES Clc1ccc(s1)C(=O)N[C@@H]1CN(C[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O)C(=O)N1CCCC1
Show InChI InChI=1S/C26H26ClN5O4S/c27-22-11-10-21(37-22)25(35)29-20-16-31(26(36)30-12-3-4-13-30)15-19(20)28-24(34)17-6-8-18(9-7-17)32-14-2-1-5-23(32)33/h1-2,5-11,14,19-20H,3-4,12-13,15-16H2,(H,28,34)(H,29,35)/t19-,20+/m0/s1
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Article
PubMed
1.70n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 5041-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.020
BindingDB Entry DOI: 10.7270/Q23J3CPQ
More data for this
Ligand-Target Pair