BDBM50218340 CHEMBL391723::N1-[4-phenyl-5-(6-oxo-6,7-dihydro-5H-[1,2,4]-triazolo[3,4-b][1,3,4]thiadiazin-3-yl)-2-thienyl]-acetamide

SMILES: CC(=O)Nc1cc(c(s1)-c1nnc2SCC(=O)Nn12)-c1ccccc1

InChI Key: InChIKey=KLEHZMSJCLNMTM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50218340 (CHEMBL391723 | N1-[4-phenyl-5-(6-oxo-6,7-dihydro-5...) Show SMILES CC(=O)Nc1cc(c(s1)-c1nnc2SCC(=O)Nn12)-c1ccccc1 Show InChI InChI=1S/C16H13N5O2S2/c1-9(22)17-13-7-11(10-5-3-2-4-6-10)14(25-13)15-18-19-16-21(15)20-12(23)8-24-16/h2-7H,8H2,1H3,(H,17,22)(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	418	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Cdk5/p25				Bioorg Med Chem 15: 6397-406 (2007) Article DOI: 10.1016/j.bmc.2007.06.053 BindingDB Entry DOI: 10.7270/Q2JS9RP0
					More data for this Ligand-Target Pair