BDBM50219223 1-(10H-phenothiazin-10-yl)-4-phenylbutan-1-one::CHEMBL394755

SMILES: O=C(CCCc1ccccc1)N1c2ccccc2Sc2ccccc12

InChI Key: InChIKey=IDGMQHJPMVCZGQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholinesterases (Homo sapiens (Human))	BDBM50219223 (1-(10H-phenothiazin-10-yl)-4-phenylbutan-1-one | C...) Show SMILES O=C(CCCc1ccccc1)N1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C22H19NOS/c24-22(16-8-11-17-9-2-1-3-10-17)23-18-12-4-6-14-20(18)25-21-15-7-5-13-19(21)23/h1-7,9-10,12-15H,8,11,16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalhousie University Curated by ChEMBL					Assay Description Inhibition of human plasma BuChE activity				Bioorg Med Chem 15: 6367-78 (2007) Article DOI: 10.1016/j.bmc.2007.06.060 BindingDB Entry DOI: 10.7270/Q2NC60XP
					More data for this Ligand-Target Pair
Histamine H2 Receptor (Homo sapiens (Human))	BDBM50219223 (1-(10H-phenothiazin-10-yl)-4-phenylbutan-1-one | C...) Show SMILES O=C(CCCc1ccccc1)N1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C22H19NOS/c24-22(16-8-11-17-9-2-1-3-10-17)23-18-12-4-6-14-20(18)25-21-15-7-5-13-19(21)23/h1-7,9-10,12-15H,8,11,16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Dalhousie University Curated by ChEMBL					Assay Description Antagonist activity at histamine H2 receptor (unknown origin) by PDSP assay				Bioorg Med Chem Lett 23: 3822-5 (2013) Article DOI: 10.1016/j.bmcl.2013.04.082 BindingDB Entry DOI: 10.7270/Q2H133DC
					More data for this Ligand-Target Pair