BDBM50219459 2-(2,3-dichlorobenzyl)-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol::CHEMBL237807

SMILES: COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cccc(Cl)c1Cl)C(F)(F)F

InChI Key: InChIKey=RRDSVYGZMKNAFC-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219459   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50219459 (2-(2,3-dichlorobenzyl)-1,1,1-trifluoro-4-(5-fluoro...) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cccc(Cl)c1Cl)C(F)(F)F |w:13.14| Show InChI InChI=1S/C20H20Cl2F4O2/c1-18(2,14-9-13(23)7-8-16(14)28-3)11-19(27,20(24,25)26)10-12-5-4-6-15(21)17(12)22/h4-9,27H,10-11H2,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of TAMRA labeled mifepristone at human mineralocorticoid receptor in insect cell				Bioorg Med Chem Lett 17: 5025-31 (2007) Article DOI: 10.1016/j.bmcl.2007.07.031 BindingDB Entry DOI: 10.7270/Q2G73FJ2
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50219459 (2-(2,3-dichlorobenzyl)-1,1,1-trifluoro-4-(5-fluoro...) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cccc(Cl)c1Cl)C(F)(F)F |w:13.14| Show InChI InChI=1S/C20H20Cl2F4O2/c1-18(2,14-9-13(23)7-8-16(14)28-3)11-19(27,20(24,25)26)10-12-5-4-6-15(21)17(12)22/h4-9,27H,10-11H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of TAMRA labeled Dexamethasone at human progesterone receptor in insect cell				Bioorg Med Chem Lett 17: 5025-31 (2007) Article DOI: 10.1016/j.bmcl.2007.07.031 BindingDB Entry DOI: 10.7270/Q2G73FJ2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50219459 (2-(2,3-dichlorobenzyl)-1,1,1-trifluoro-4-(5-fluoro...) Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cccc(Cl)c1Cl)C(F)(F)F |w:13.14| Show InChI InChI=1S/C20H20Cl2F4O2/c1-18(2,14-9-13(23)7-8-16(14)28-3)11-19(27,20(24,25)26)10-12-5-4-6-15(21)17(12)22/h4-9,27H,10-11H2,1-3H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cell				Bioorg Med Chem Lett 17: 5025-31 (2007) Article DOI: 10.1016/j.bmcl.2007.07.031 BindingDB Entry DOI: 10.7270/Q2G73FJ2
					More data for this Ligand-Target Pair