BDBM50220012 (5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3-triazol-1-ylmethyl)-1,3-oxazolidin-2-one::CHEMBL394864

SMILES: Fc1cc(ccc1-c1cccnc1)N1C[C@H](Cn2ccnn2)OC1=O

InChI Key: InChIKey=URZMJARQWGKHCG-AWEZNQCLSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50220012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50220012 ((5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3...) Show SMILES Fc1cc(ccc1-c1cccnc1)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C17H14FN5O2/c18-16-8-13(3-4-15(16)12-2-1-5-19-9-12)23-11-14(25-17(23)24)10-22-7-6-20-21-22/h1-9,14H,10-11H2/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP2C9				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50220012 ((5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3...) Show SMILES Fc1cc(ccc1-c1cccnc1)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C17H14FN5O2/c18-16-8-13(3-4-15(16)12-2-1-5-19-9-12)23-11-14(25-17(23)24)10-22-7-6-20-21-22/h1-9,14H,10-11H2/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP2C19				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50220012 ((5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3...) Show SMILES Fc1cc(ccc1-c1cccnc1)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C17H14FN5O2/c18-16-8-13(3-4-15(16)12-2-1-5-19-9-12)23-11-14(25-17(23)24)10-22-7-6-20-21-22/h1-9,14H,10-11H2/t14-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP2D6				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50220012 ((5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3...) Show SMILES Fc1cc(ccc1-c1cccnc1)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C17H14FN5O2/c18-16-8-13(3-4-15(16)12-2-1-5-19-9-12)23-11-14(25-17(23)24)10-22-7-6-20-21-22/h1-9,14H,10-11H2/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP3A4				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair
Cytochrome P450 1A (Homo sapiens (Human))	BDBM50220012 ((5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3...) Show SMILES Fc1cc(ccc1-c1cccnc1)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C17H14FN5O2/c18-16-8-13(3-4-15(16)12-2-1-5-19-9-12)23-11-14(25-17(23)24)10-22-7-6-20-21-22/h1-9,14H,10-11H2/t14-/m0/s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP1A2				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair