BDBM50220066 6,7-dihydro-1H-cyclopenta[a]pyrrolo[3,4-c]carbazole-1,3,4-(2H,5H)-trione::CHEMBL395016

SMILES: O=C1CCc2c1c1C(=O)NC(=O)c1c1c2[nH]c2ccccc12

InChI Key: InChIKey=QZATXSOYNSMLJE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50220066 (6,7-dihydro-1H-cyclopenta[a]pyrrolo[3,4-c]carbazol...) Show SMILES O=C1CCc2c1c1C(=O)NC(=O)c1c1c2[nH]c2ccccc12 Show InChI InChI=1S/C17H10N2O3/c20-10-6-5-8-11(10)13-14(17(22)19-16(13)21)12-7-3-1-2-4-9(7)18-15(8)12/h1-4,18H,5-6H2,(H,19,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Université Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1 expressed in Sf9 cells				J Med Chem 50: 4669-80 (2007) Article DOI: 10.1021/jm070664k BindingDB Entry DOI: 10.7270/Q2P55N7F
					More data for this Ligand-Target Pair