BDBM50220159 CHEMBL389589::N-[3'-fluoro-4'-(trifluoromethyl)-1,1'-biphenyl-4-yl]sulfamide::N-[3'-fluoro-4'-(trifluoromethyl)-4-biphenylyl]sulfamide

SMILES: NS(=O)(=O)Nc1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F

InChI Key: InChIKey=GEMSMTTWZNDMSW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50220159 (CHEMBL389589 | N-[3'-fluoro-4'-(trifluoromethyl)-1...) Show SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C13H10F4N2O2S/c14-12-7-9(3-6-11(12)13(15,16)17)8-1-4-10(5-2-8)19-22(18,20)21/h1-7,19H,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Shizuoka Curated by ChEMBL					Assay Description Inhibition of microtubule-stimulated recombinant Eg5 (unknown origin) assessed as inhibition ATP hydrolysis by luminescent kinase assay				Bioorg Med Chem Lett 19: 1058-61 (2009) Article DOI: 10.1016/j.bmcl.2009.01.018 BindingDB Entry DOI: 10.7270/Q20R9P8G
					More data for this Ligand-Target Pair
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50220159 (CHEMBL389589 | N-[3'-fluoro-4'-(trifluoromethyl)-1...) Show SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C13H10F4N2O2S/c14-12-7-9(3-6-11(12)13(15,16)17)8-1-4-10(5-2-8)19-22(18,20)21/h1-7,19H,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair