Found 3 hits for monomerid = 50220410 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220410
(CHEMBL62115)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)c2cnccn2)cc1 Show InChI InChI=1S/C24H32N4O3/c1-2-3-4-6-23(29)20-7-9-21(10-8-20)31-18-5-13-27-14-16-28(17-15-27)24(30)22-19-25-11-12-26-22/h7-12,19H,2-6,13-18H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50220410
(CHEMBL62115)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)c2cnccn2)cc1 Show InChI InChI=1S/C24H32N4O3/c1-2-3-4-6-23(29)20-7-9-21(10-8-20)31-18-5-13-27-14-16-28(17-15-27)24(30)22-19-25-11-12-26-22/h7-12,19H,2-6,13-18H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 2.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for the human Histamine H1 Receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Homo sapiens (Human)) | BDBM50220410
(CHEMBL62115)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)c2cnccn2)cc1 Show InChI InChI=1S/C24H32N4O3/c1-2-3-4-6-23(29)20-7-9-21(10-8-20)31-18-5-13-27-14-16-28(17-15-27)24(30)22-19-25-11-12-26-22/h7-12,19H,2-6,13-18H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 4.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for the human Histamine H2 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this Ligand-Target Pair | |