BDBM50220909 3,9-dimethyl-2H-pyrazolo[4,3-c]quinolin-4(5H)-one::CHEMBL403133

SMILES: Cc1[nH]nc2c1c(=O)[nH]c1cccc(C)c21

InChI Key: InChIKey=AMLBHIJEXWWWIE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220909   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50220909 (3,9-dimethyl-2H-pyrazolo[4,3-c]quinolin-4(5H)-one ...) Show SMILES Cc1[nH]nc2c1c(=O)[nH]c1cccc(C)c21 Show InChI InChI=1S/C12H11N3O/c1-6-4-3-5-8-9(6)11-10(12(16)13-8)7(2)14-15-11/h3-5H,1-2H3,(H,13,16)(H,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Chk1 by fluorescence assay				Bioorg Med Chem Lett 17: 5989-94 (2007) Article DOI: 10.1016/j.bmcl.2007.07.051 BindingDB Entry DOI: 10.7270/Q2K93775
					More data for this Ligand-Target Pair