BDBM50220980 CHEMBL305248

SMILES: [H][C@@]12CN(CCCNc3c4CCCCCc4nc4ccccc34)C[C@]1([H])[C@H]2NC(=O)OC(C)(C)C

InChI Key: InChIKey=ZCZPKLVCUBJXHY-ZZYHAFTGSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220980   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50220980 (CHEMBL305248) Show SMILES [H][C@@]12CN(CCCNc3c4CCCCCc4nc4ccccc34)C[C@]1([H])[C@H]2NC(=O)OC(C)(C)C Show InChI InChI=1S/C27H38N4O2/c1-27(2,3)33-26(32)30-25-20-16-31(17-21(20)25)15-9-14-28-24-18-10-5-4-6-12-22(18)29-23-13-8-7-11-19(23)24/h7-8,11,13,20-21,25H,4-6,9-10,12,14-17H2,1-3H3,(H,28,29)(H,30,32)/t20-,21+,25+	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards cloned human H3L receptor				Bioorg Med Chem Lett 13: 2131-5 (2003) BindingDB Entry DOI: 10.7270/Q2K073N9
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50220980 (CHEMBL305248) Show SMILES [H][C@@]12CN(CCCNc3c4CCCCCc4nc4ccccc34)C[C@]1([H])[C@H]2NC(=O)OC(C)(C)C Show InChI InChI=1S/C27H38N4O2/c1-27(2,3)33-26(32)30-25-20-16-31(17-21(20)25)15-9-14-28-24-18-10-5-4-6-12-22(18)29-23-13-8-7-11-19(23)24/h7-8,11,13,20-21,25H,4-6,9-10,12,14-17H2,1-3H3,(H,28,29)(H,30,32)/t20-,21+,25+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards rat cortical Histamine H3 receptor				Bioorg Med Chem Lett 13: 2131-5 (2003) BindingDB Entry DOI: 10.7270/Q2K073N9
					More data for this Ligand-Target Pair