BDBM50221106 2-(4-(methylsulfonyl)phenyl)-3-p-tolylthiazolidin-4-one::CHEMBL399879

SMILES: Cc1ccc(cc1)N1C(SCC1=O)c1ccc(cc1)S(C)(=O)=O

InChI Key: InChIKey=HYUCGYXDBKSSCK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclooxygenase (Homo sapiens (Human))	BDBM50221106 (2-(4-(methylsulfonyl)phenyl)-3-p-tolylthiazolidin-...) Show SMILES Cc1ccc(cc1)N1C(SCC1=O)c1ccc(cc1)S(C)(=O)=O |w:8.14| Show InChI InChI=1S/C17H17NO3S2/c1-12-3-7-14(8-4-12)18-16(19)11-22-17(18)13-5-9-15(10-6-13)23(2,20)21/h3-10,17H,11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of COX2				Bioorg Med Chem Lett 17: 5634-7 (2007) Article DOI: 10.1016/j.bmcl.2007.07.084 BindingDB Entry DOI: 10.7270/Q22807BC
					More data for this Ligand-Target Pair
Cyclooxygenase-1 (COX-1) (Homo sapiens (Human))	BDBM50221106 (2-(4-(methylsulfonyl)phenyl)-3-p-tolylthiazolidin-...) Show SMILES Cc1ccc(cc1)N1C(SCC1=O)c1ccc(cc1)S(C)(=O)=O |w:8.14| Show InChI InChI=1S/C17H17NO3S2/c1-12-3-7-14(8-4-12)18-16(19)11-22-17(18)13-5-9-15(10-6-13)23(2,20)21/h3-10,17H,11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shaheed Beheshti University of Medical Sciences Curated by ChEMBL					Assay Description Inhibition of COX1				Bioorg Med Chem Lett 17: 5634-7 (2007) Article DOI: 10.1016/j.bmcl.2007.07.084 BindingDB Entry DOI: 10.7270/Q22807BC
					More data for this Ligand-Target Pair