BDBM50221371 CHEMBL241660::N-(4-{4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl}butyl)thiophen-2-carboxamide

SMILES: Clc1ccc(cc1)C(N1CCN(CCCCNC(=O)c2cccs2)CC1)c1ccccc1

InChI Key: InChIKey=CUKXVIBQJUBHRB-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50221371 (CHEMBL241660 | N-(4-{4-[(4-chlorophenyl)phenylmeth...) Show SMILES Clc1ccc(cc1)C(N1CCN(CCCCNC(=O)c2cccs2)CC1)c1ccccc1 |w:7.28| Show InChI InChI=1S/C26H30ClN3OS/c27-23-12-10-22(11-13-23)25(21-7-2-1-3-8-21)30-18-16-29(17-19-30)15-5-4-14-28-26(31)24-9-6-20-32-24/h1-3,6-13,20,25H,4-5,14-19H2,(H,28,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 7258-73 (2007) Article DOI: 10.1016/j.bmc.2007.08.034 BindingDB Entry DOI: 10.7270/Q21C1WMX
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50221371 (CHEMBL241660 | N-(4-{4-[(4-chlorophenyl)phenylmeth...) Show SMILES Clc1ccc(cc1)C(N1CCN(CCCCNC(=O)c2cccs2)CC1)c1ccccc1 |w:7.28| Show InChI InChI=1S/C26H30ClN3OS/c27-23-12-10-22(11-13-23)25(21-7-2-1-3-8-21)30-18-16-29(17-19-30)15-5-4-14-28-26(31)24-9-6-20-32-24/h1-3,6-13,20,25H,4-5,14-19H2,(H,28,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor expressed in HEK cells				Bioorg Med Chem 15: 7258-73 (2007) Article DOI: 10.1016/j.bmc.2007.08.034 BindingDB Entry DOI: 10.7270/Q21C1WMX
					More data for this Ligand-Target Pair