BindingDB logo
myBDB logout

null

SMILES: ONC(=O)CCCCCCc1ncc(o1)-c1ccc(cc1)-c1ccc(Cl)cc1

InChI Key: InChIKey=GKBWWQHTKOYJBI-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222341   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1/2


(Homo sapiens (Human))		BDBM50222341
PNG
(CHEMBL124650)
Show SMILES ONC(=O)CCCCCCc1ncc(o1)-c1ccc(cc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C22H23ClN2O3/c23-19-13-11-17(12-14-19)16-7-9-18(10-8-16)20-15-24-22(28-20)6-4-2-1-3-5-21(26)25-27/h7-15,27H,1-6H2,(H,25,26)
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 6.80n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cells

Bioorg Med Chem Lett 13: 3817-20 (2003)


BindingDB Entry DOI: 10.7270/Q23F4RVV
More data for this
Ligand-Target Pair