BDBM50222979 3,6-diethyl-5-(4-methylpyridin-2-yloxy)-N-(1-phenylethyl)pyrazin-2-amine::CHEMBL401327

SMILES: CCc1nc(Oc2cc(C)ccn2)c(CC)nc1NC(C)c1ccccc1

InChI Key: InChIKey=SINICVYFWKASAP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222979   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50222979 (3,6-diethyl-5-(4-methylpyridin-2-yloxy)-N-(1-pheny...) Show SMILES CCc1nc(Oc2cc(C)ccn2)c(CC)nc1NC(C)c1ccccc1 |w:19.21| Show InChI InChI=1S/C22H26N4O/c1-5-18-21(24-16(4)17-10-8-7-9-11-17)25-19(6-2)22(26-18)27-20-14-15(3)12-13-23-20/h7-14,16H,5-6H2,1-4H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-o-CRF from CRF1 receptor in IMR32 cells				Bioorg Med Chem Lett 17: 6250-6 (2007) Article DOI: 10.1016/j.bmcl.2007.09.008 BindingDB Entry DOI: 10.7270/Q2F76C8G
					More data for this Ligand-Target Pair