BDBM50223608 3-bromo-5-ethyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL398670

SMILES: CCc1cc(NCc2cccnc2)n2ncc(Br)c2n1

InChI Key: InChIKey=FKICFRRAAYFTDU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50223608 (3-bromo-5-ethyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5...) Show SMILES CCc1cc(NCc2cccnc2)n2ncc(Br)c2n1 Show InChI InChI=1S/C14H14BrN5/c1-2-11-6-13(17-8-10-4-3-5-16-7-10)20-14(19-11)12(15)9-18-20/h3-7,9,17H,2,8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Bioorg Med Chem Lett 17: 6220-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.017 BindingDB Entry DOI: 10.7270/Q27M07ND
					More data for this Ligand-Target Pair