BDBM50223642 CHEMBL7821

SMILES: CN1CCN(CC1)C1=Cc2ccccc2Cc2ccccc12

InChI Key: InChIKey=CQBZYAFJUWYRHM-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50223642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50223642 (CHEMBL7821) Show SMILES CN1CCN(CC1)C1=Cc2ccccc2Cc2ccccc12 |t:8| Show InChI InChI=1S/C20H22N2/c1-21-10-12-22(13-11-21)20-15-17-7-3-2-6-16(17)14-18-8-4-5-9-19(18)20/h2-9,15H,10-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	808	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of 3[H]spiroperidol from Dopamine receptor in rat brain				J Med Chem 25: 855-8 (1982) BindingDB Entry DOI: 10.7270/Q2N018R2
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50223642 (CHEMBL7821) Show SMILES CN1CCN(CC1)C1=Cc2ccccc2Cc2ccccc12 |t:8| Show InChI InChI=1S/C20H22N2/c1-21-10-12-22(13-11-21)20-15-17-7-3-2-6-16(17)14-18-8-4-5-9-19(18)20/h2-9,15H,10-14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Concentration required (in vitro) to displace 50% specific binding of [3H]clozapine to Muscarinic acetylcholine receptor in rat brain				J Med Chem 24: 1021-6 (1981) BindingDB Entry DOI: 10.7270/Q2348NKF
					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50223642 (CHEMBL7821) Show SMILES CN1CCN(CC1)C1=Cc2ccccc2Cc2ccccc12 |t:8| Show InChI InChI=1S/C20H22N2/c1-21-10-12-22(13-11-21)20-15-17-7-3-2-6-16(17)14-18-8-4-5-9-19(18)20/h2-9,15H,10-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	808	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Relative affinity for dopamine receptor by displacement of [3H]spiroperidol (2.2 nM) from (in vitro) dopamine binding sites in rat caudate nuclei				J Med Chem 24: 1021-6 (1981) BindingDB Entry DOI: 10.7270/Q2348NKF
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (RAT)	BDBM50223642 (CHEMBL7821) Show SMILES CN1CCN(CC1)C1=Cc2ccccc2Cc2ccccc12 |t:8| Show InChI InChI=1S/C20H22N2/c1-21-10-12-22(13-11-21)20-15-17-7-3-2-6-16(17)14-18-8-4-5-9-19(18)20/h2-9,15H,10-14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for its ability to displace 3[H] clozapine from Muscarinic acetylcholine receptor in rat brain				J Med Chem 25: 855-8 (1982) BindingDB Entry DOI: 10.7270/Q2N018R2
					More data for this Ligand-Target Pair