BDBM50224757 4-(6-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-yl)-N,N-dimethylbenzenamine::CHEMBL395839

SMILES: COc1ccc(cc1)-c1cnc2nc([nH]c2c1)-c1ccc(cc1)N(C)C

InChI Key: InChIKey=LMDQKFVXYFATNQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50224757   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50224757 (4-(6-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-...) Show SMILES COc1ccc(cc1)-c1cnc2nc([nH]c2c1)-c1ccc(cc1)N(C)C Show InChI InChI=1S/C21H20N4O/c1-25(2)17-8-4-15(5-9-17)20-23-19-12-16(13-22-21(19)24-20)14-6-10-18(26-3)11-7-14/h4-13H,1-3H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of Aurora A				Eur J Med Chem 46: 77-94 (2010) Article DOI: 10.1016/j.ejmech.2010.10.017 BindingDB Entry DOI: 10.7270/Q25X296N
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50224757 (4-(6-(4-methoxyphenyl)-3H-imidazo[4,5-b]pyridin-2-...) Show SMILES COc1ccc(cc1)-c1cnc2nc([nH]c2c1)-c1ccc(cc1)N(C)C Show InChI InChI=1S/C21H20N4O/c1-25(2)17-8-4-15(5-9-17)20-23-19-12-16(13-22-21(19)24-20)14-6-10-18(26-3)11-7-14/h4-13H,1-3H3,(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of aurora A kinase				Bioorg Med Chem Lett 17: 6567-71 (2007) Article DOI: 10.1016/j.bmcl.2007.09.076 BindingDB Entry DOI: 10.7270/Q27D2TVT
					More data for this Ligand-Target Pair