BDBM50227280 CHEMBL15247

SMILES: CCNCC1CCN(C1)c1c(F)c(N)c2c(c1F)n(cc(C(O)=O)c2=O)C1CC1

InChI Key: InChIKey=VXFMLSPHMLXTEK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Gyrase (Escherichia coli (strain K12))	BDBM50227280 (CHEMBL15247) Show SMILES CCNCC1CCN(C1)c1c(F)c(N)c2c(c1F)n(cc(C(O)=O)c2=O)C1CC1 Show InChI InChI=1S/C20H24F2N4O3/c1-2-24-7-10-5-6-25(8-10)18-14(21)16(23)13-17(15(18)22)26(11-3-4-11)9-12(19(13)27)20(28)29/h9-11,24H,2-8,23H2,1H3,(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description 50% inhibitory concentration against DNA-gyrase				J Med Chem 31: 503-6 (1988) BindingDB Entry DOI: 10.7270/Q23B62BK
					More data for this Ligand-Target Pair