BDBM50227281 CHEMBL359193

SMILES: CCNCC1CCN(C1)c1c(F)c(NC)c2c(c1F)n(cc(C(O)=O)c2=O)C1CC1

InChI Key: InChIKey=IWVJNYOIZBVCKG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Gyrase (Escherichia coli (strain K12))	BDBM50227281 (CHEMBL359193) Show SMILES CCNCC1CCN(C1)c1c(F)c(NC)c2c(c1F)n(cc(C(O)=O)c2=O)C1CC1 Show InChI InChI=1S/C21H26F2N4O3/c1-3-25-8-11-6-7-26(9-11)19-15(22)17(24-2)14-18(16(19)23)27(12-4-5-12)10-13(20(14)28)21(29)30/h10-12,24-25H,3-9H2,1-2H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description 50% inhibitory concentration against DNA-gyrase				J Med Chem 31: 503-6 (1988) BindingDB Entry DOI: 10.7270/Q23B62BK
					More data for this Ligand-Target Pair