BDBM50227554 2-chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate::CHEMBL399685

SMILES: Clc1ccccc1COC(=O)c1cccc(=O)[nH]1

InChI Key: InChIKey=GBDUKEUKPOMNDD-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50227554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interstitial collagenase (Homo sapiens (Human))	BDBM50227554 (2-chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxy...) Show SMILES Clc1ccccc1COC(=O)c1cccc(=O)[nH]1 Show InChI InChI=1S/C13H10ClNO3/c14-10-5-2-1-4-9(10)8-18-13(17)11-6-3-7-12(16)15-11/h1-7H,8H2,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
North Dakota State University Curated by ChEMBL					Assay Description Inhibition of MMP1				Bioorg Med Chem Lett 17: 6864-70 (2008) Article DOI: 10.1016/j.bmcl.2007.10.020 BindingDB Entry DOI: 10.7270/Q2C24X80
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50227554 (2-chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxy...) Show SMILES Clc1ccccc1COC(=O)c1cccc(=O)[nH]1 Show InChI InChI=1S/C13H10ClNO3/c14-10-5-2-1-4-9(10)8-18-13(17)11-6-3-7-12(16)15-11/h1-7H,8H2,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
North Dakota State University Curated by ChEMBL					Assay Description Inhibition of MMP9				Bioorg Med Chem Lett 17: 6864-70 (2008) Article DOI: 10.1016/j.bmcl.2007.10.020 BindingDB Entry DOI: 10.7270/Q2C24X80
					More data for this Ligand-Target Pair
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50227554 (2-chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxy...) Show SMILES Clc1ccccc1COC(=O)c1cccc(=O)[nH]1 Show InChI InChI=1S/C13H10ClNO3/c14-10-5-2-1-4-9(10)8-18-13(17)11-6-3-7-12(16)15-11/h1-7H,8H2,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
North Dakota State University Curated by ChEMBL					Assay Description Inhibition of MMP12				Bioorg Med Chem Lett 17: 6864-70 (2008) Article DOI: 10.1016/j.bmcl.2007.10.020 BindingDB Entry DOI: 10.7270/Q2C24X80
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227554 (2-chlorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxy...) Show SMILES Clc1ccccc1COC(=O)c1cccc(=O)[nH]1 Show InChI InChI=1S/C13H10ClNO3/c14-10-5-2-1-4-9(10)8-18-13(17)11-6-3-7-12(16)15-11/h1-7H,8H2,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
North Dakota State University Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6864-70 (2008) Article DOI: 10.1016/j.bmcl.2007.10.020 BindingDB Entry DOI: 10.7270/Q2C24X80
					More data for this Ligand-Target Pair