BDBM50227601 6-mercapto-pyridine-2-carboxylic acid biphenyl-3-ylmethyl ester::CHEMBL251426

SMILES: O=C(OCc1cccc(c1)-c1ccccc1)c1cccc(=S)[nH]1

InChI Key: InChIKey=KUFQPJWHPFBJRV-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50227601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50227601 (6-mercapto-pyridine-2-carboxylic acid biphenyl-3-y...) Show SMILES O=C(OCc1cccc(c1)-c1ccccc1)c1cccc(=S)[nH]1 Show InChI InChI=1S/C19H15NO2S/c21-19(17-10-5-11-18(23)20-17)22-13-14-6-4-9-16(12-14)15-7-2-1-3-8-15/h1-12H,13H2,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
North Dakota State University Curated by ChEMBL					Assay Description Inhibition of MMP9				Bioorg Med Chem Lett 17: 6864-70 (2008) Article DOI: 10.1016/j.bmcl.2007.10.020 BindingDB Entry DOI: 10.7270/Q2C24X80
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50227601 (6-mercapto-pyridine-2-carboxylic acid biphenyl-3-y...) Show SMILES O=C(OCc1cccc(c1)-c1ccccc1)c1cccc(=S)[nH]1 Show InChI InChI=1S/C19H15NO2S/c21-19(17-10-5-11-18(23)20-17)22-13-14-6-4-9-16(12-14)15-7-2-1-3-8-15/h1-12H,13H2,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
North Dakota State University Curated by ChEMBL					Assay Description Inhibition of MMP1				Bioorg Med Chem Lett 17: 6864-70 (2008) Article DOI: 10.1016/j.bmcl.2007.10.020 BindingDB Entry DOI: 10.7270/Q2C24X80
					More data for this Ligand-Target Pair
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50227601 (6-mercapto-pyridine-2-carboxylic acid biphenyl-3-y...) Show SMILES O=C(OCc1cccc(c1)-c1ccccc1)c1cccc(=S)[nH]1 Show InChI InChI=1S/C19H15NO2S/c21-19(17-10-5-11-18(23)20-17)22-13-14-6-4-9-16(12-14)15-7-2-1-3-8-15/h1-12H,13H2,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
North Dakota State University Curated by ChEMBL					Assay Description Inhibition of MMP12				Bioorg Med Chem Lett 17: 6864-70 (2008) Article DOI: 10.1016/j.bmcl.2007.10.020 BindingDB Entry DOI: 10.7270/Q2C24X80
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227601 (6-mercapto-pyridine-2-carboxylic acid biphenyl-3-y...) Show SMILES O=C(OCc1cccc(c1)-c1ccccc1)c1cccc(=S)[nH]1 Show InChI InChI=1S/C19H15NO2S/c21-19(17-10-5-11-18(23)20-17)22-13-14-6-4-9-16(12-14)15-7-2-1-3-8-15/h1-12H,13H2,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
North Dakota State University Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6864-70 (2008) Article DOI: 10.1016/j.bmcl.2007.10.020 BindingDB Entry DOI: 10.7270/Q2C24X80
					More data for this Ligand-Target Pair